Laboratory Scientist PHE
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Research & Evaluation department, based at UKHSA Porton, is the UK’s largest capability for the handling of dangerous human pathogens and animalmodelling of infectious diseases. The capability is used to understand pathogenesis and undertake pre-clinical development and assessment of new vaccines and therapeutics. The capability is also used to undertake studies in microbiological aerobiology, decontamination and detection, and to develop diagnostic assays for clinical use. Studies are focussed on high priority activities including: SARS-CoV-2, Ebola, Zika, Crimean Congo Haemorrhagic Fever, Q Fever, Anthrax, Melioidosis, Clostridium difficile-Associated Disease, Tuberculosis, Monkeypox, Influenza, Pertussis, Meningococcal disease, Group B Streptococcal disease, Legionnaires Disease, Healthcare Acquired Infections, Anti-Microbial Resistance, etc.
Job description
The post holder will play a key role in an internationally recognised team contributing to global TB vaccine and drug initiatives. The team are responsible for the delivery of the scientific and technical activities associated with the use of advanced in vivo models of M. tuberculosis infection for the evaluation of novel TB vaccine strategies and therapeutics.
The post holder must be already/ willing to be BCG vaccinated as this is required for this role.
The post holder will assist with the evaluation of novel vaccines and therapeutics in the following ways:
✔Using immunological techniques such as ELISA, Flow cytometry and PCR.
✔Using microbiological techniques such as plating of bacteria/tissue samples and counting CFUs.
✔Using the above techniques in a containment level 3 environment.
✔Assisting with the preparation for individual studies
✔Assist with data analysis and presentation
In addition, the post holder will:
✔Assist with ongoing pandemic by contributing to SARS-CoV-2 tasks as directed by line manager.
