The VALIDATE Network - Vaccine development for complex intracellular neglected pathogens
Postdoctoral Fellowship in Computational Immunology - UCT, South Africa, 2020
Deadline for applications: 15 September 2020
The South African Tuberculosis Vaccine Initiative performs cutting edge clinical and immunological research in TB pathogenesis, biomarker development and clinical vaccine development. We are inviting applications for a postdoctoral fellowship in computational immunology to conduct research on a large project aimed at understanding the pathogenesis of subclinical TB and identifying immune correlates of protection against TB. The project is part of an international effort to discover immune correlates of protection against TB in the context of two phase 2b clinical trials of TB vaccination that demonstrated protection. The fellow will be based in Cape Town, but the project may include activity-related travel to collaborating institutes. The successful candidate will be part of the SATVI ComputationalImmunology team and will contribute to design, development, and performance of computational and statistical analyses of host RNA-seq data within the context of complementary immunological outcomes. Responsibilities will include applying and developing approaches and computational models for identifying and validating candidate correlates that allow prediction of protection against TB.
•Ph.D. degree within the last 5 years in bioinformatics, biostatistics or computational biology, or PhD in biological sciences with at least 3 years of relevant bioinformatics or computational biology experience.
•Working proficiency in UNIX/Linux and R and/or Python programming.
•Strong skills in the application of computational and statistical analytical techniques with a focus on high-dimensional and multivariate data analysis.
•Demonstrated solid scientific proficiency, creativity, critical thinking ability to collaborate effectively with others, and independent thought processes.
•Authorship of peer-reviewed publications related to bioinformatics, computational biology or immunology.
•Ability to handle multiple projects and priorities with exceptional organizational and time management skills.