Thao-Thy Pham
Post-Doctoral Researcher Institute of Tropical Medicine Antwerp, Belgium Email: thaothypham@itg.be
VALIDATE Role: Network Associate
Research Keywords: Leishmania, T Cell Immunity, Clinical Studies, Spatial Transcriptomics, Single Cell Transcriptomics, Malaria, Cutaneous Leishmaniasis, Visceral Leishmaniasis, Immunological Biomarkers, Diagnostics, Vaccinology, Vaccinome, Epitope Recognition, Epitope Presentation
Biography: Currently, I am coordinating the Spatial CL study (Clinicaltrials.gov NCT05332093), wherein we aim to investigate the host-parasite interactions in the different clinical presentations of Ethiopian cutaneous leishmaniasis in a spatial and single-cell resolved manner. In parallel, I am involved in the CPS study (Clinicaltrials.gov NCT05602610) where we will assess immunological biomarkers to predict treatment outcome for Ethiopian visceral leishmaniasis to eventually wheel into point-of-care diagnostic assays. My main research focuses on identifying Leishmania epitopes capable of eliciting protective T cell responses, thereby potentially qualifying them as vaccine candidates. For this, I am developing a methodological pipeline including advanced T-cell focused assays.
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