Madhurima Roy

Madhurima Roy

Research Associate/Project Research Scientist I

Institute of Post-Graduate Medical Education and Research (IPGMER), India

Email: madsroy296@gmail.com

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords:

Post Kala-azar Dermal Leishmaniasis, Cutaneous Leishmaniasis, Immunopathogenesis, Host-Pathogen Interactions

 

Biography:

I am a Research Associate at the Institute of Post Graduate Medical Education & Research (IPGME&R), Kolkata, with a research focus on the immunopathology of neglected tropical diseases, particularly Post Kala-azar Dermal Leishmaniasis (PKDL). I hold a Ph.D. in Biotechnology from the University of Calcutta and has been awarded competitive fellowships from the University Grants Commission (UGC), India.

My current work integrates spatial immune profiling and immune cell dynamics in host-pathogen interactions in chronic dermal lesions, especially with regard to skin hypopigmentation and pathogen control. Previously, I have contributed to clinical diagnostic assay development through multi-institutional projects involving partners in India, Bangladesh, and Germany, with research experience spanning both field and laboratory settings, and served as a visiting researcher at the University of Leipzig under the DST-DAAD exchange programme. My broader interests include translational clinical research and collaborative capacity-building in global health.

 

Related Websites:

LinkedIn

 

Key Publications:

  • Transdifferentiation of neutrophils facilitates establishment of infection by Leishmania donovani parasites. Roy M, Bagchi A, Karmakar C, Chatterjee M. Infect Immun. 2025, 93:e0040924.
  • Mapping the immune landscape in South Asian post kala-azar dermal leishmaniasis. Roy M, Sengupta R, Chatterjee M. Ann Med Sci Res 2025;4:S65-73.
  • Role of neutrophils in the pathogenesis of Post Kala-azar Dermal Leishmaniasis (PKDL). Roy M, Sengupta R, Chakraborty BC, Chatterjee U, Stebut EV, Kaye PM, Chatterjee M. PLoS Negl Trop Dis. 2024;18:e0012655. doi: 10.1371/journal.pntd.0012655.
  • Evaluation of Recombinase Polymerase Amplification assay for monitoring parasite load in patients with kala-azar and post kala-azar dermal leishmaniasis. Roy M, Ceruti A, Kobialka RM, Roy S, Sarkar D, Wahed AAE, Chatterjee M. PLoS Negl Trop Dis. 2023;17:e0011231. doi: 10.1371/journal.pntd.0011231.
  • Quantitative monitoring of experimental and human leishmaniasis employing amastigote-specific genes. Roy M, Sarkar D, Chatterjee M. Parasitology. 2022;149:1085-1093. doi: 10.1017/S0031182022000610.
  • Monitoring the Long-Term Effectiveness of Miltefosine in Indian Post-Kala-Azar Dermal Leishmaniasis. Roy S, Moulik S, Roy M, Ghosh MK, Chaudhuri SJ, Pandey DK, Jain S, Dagne DA, Chatterjee M. Am J Trop Med Hyg. 2024;110:656-662. doi: 10.4269/ajtmh.23-0197.
  • Portable smartphone-based molecular test for rapid detection of Leishmania spp. Kobialka RM, Ceruti A, Roy M, Roy S, Chowdhury R, Ghosh P, Hossain F, Weidmann M, Graf E, Bueno Alvarez J, Moreno J, Truyen U, Mondal D, Chatterjee M, Abd El Wahed A. Infection. 2024;52:1315-1324. doi: 10.1007/s15010-024-02179-z.
  • Immune dysregulation and inflammation causing hypopigmentation in post kala-azar dermal leishmaniasis: partners in crime? Sengupta R, Roy M, Dey NS, Kaye PM, Chatterjee M. Trends Parasitol. 2023;39:822-836. doi: 10.1016/j.pt.2023.07.005.
  • Role of molecular approaches to distinguish post kala-azar dermal leishmaniasis from leprosy: A case study. Roy S, Roy M, Nath S, Chaudhuri SJ, Ghosh MK, Mukherjee S, Chatterjee M. Indian J Dermatol Venereol Leprol. 2023;89:298-300. doi: 10.25259/IJDVL_415_2022.