PhD Studentship: Novel targets for overcoming antimicrobial resistance and tolerance: multikinase network signalling in Burkholderia pseudomallei

Antimicrobial resistance is a major problem for treating bacterial infections. In many bacteria, ever increasing levels of resistance are accompanied by high levels of tolerance to the few antimicrobials that they remain susceptible to, requiring long treatment courses to avoid treatment failure. This is exemplified by the pathogen Burkholderia pseudomallei, which causes the disease melioidosis that kills around 89000 people annually. A promising new way of tackling infection is to develop ways of interfering with the sensory networks that bacteria rely on for coordinating their stress responses and for controlling the traits needed for resistance, tolerance and virulence. 

The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales.

This partnership has established international, national and regional scientific networks, and widely recognised research excellence and facilities.

We aim to provide you with outstanding interdisciplinary bioscience research training, underpinned by transformative technologies.

Find out more and apply online.