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Senior Lecturer
Walter Sisulu University, South Africa
Email: mshauli@wsu.ac.za
VALIDATE Role:
Network Associate
Research Keywords:
TB, Animal Models, Cell Culture
Biography:
My main research interest is studying efficacy and toxicity of medicinal plants. Investigation of alternative solutions or therapies to eradicate TB is my work. I test medicinal plants for their immunomodulatory potential to sustain macrophages in a phenotype that is capable of destroying the bacteria (Host-pathogen interaction) and invention of new TB vaccine, using animal model.
Related Websites:
LinkedIn
Walter Sisulu University
Key Publications:
- Shauli, M. M., Macingwana, L., Rusike, c., and Mtokwana, M. WO2025027535 - extracts of Sanicula elata for use in treating pulmonary tuberculosis. WIPO-International and National Patent Collection. https://patentscope2.wipo.int WO2025027535
- Shauli, M. M., Macingwana, L., & Rusike, C. R. (2024). In vitro immunomodulation of RAW264.7 macrophages and cytotoxicity assessment of medicinal plants used traditionally to treat pulmonary tuberculosis in South Africa. https://doi.org/10.20944/preprints202401.0890.v1
- Shauli, M., Sewani-Rusike, C., Abura, S., Kolosa, I., Gondwe, M. M., Gari, M., ... & Smith, N. (2023). Acute toxicity and 28-day oral administration of Euclea natalensis extract in Swiss albino mice. The Journal of Medical Laboratory Science and Technology of South Africa, 5(1), 1-10.
- Suleman, Z., Engwa, G. A., Shauli, M., Musarurwa, H. T., Katuruza, N. A., & Sewani-Rusike, C. R. (2022). Neuroprotective effects of Lippia javanica (Burm. F.) Spreng. herbal tea infusion on lead-induced oxidative brain damage in Wistar rats. BMC Complementary Medicine and Therapies, 22(1), 4.
- Ndebia, E. J., Zweni, L., Seipone, I. D., Shauli, M Gondwe, M. (2021). Histopathology assessment of the effects of on experimentally induced reflux esophagitis. Journal of Experimental Research, 9(2).
- Mfengu, M. O., Shauli, M., Engwa, G. A., Musarurwa, H. T., & Sewani-Rusike, C. R. (2021). Lippia javanica (Zumbani) herbal tea infusion attenuates allergic airway inflammation via inhibition of Th2 cell activation and suppression of oxidative stress. BMC Complementary Medicine and Therapies, 21, 1-14.
- Tata, C. M., Sewani-Rusike, C. R., Oyedeji, O. O., Mahlakata, F., Shauli, M., & Nkeh-Chungag, B. N. (2020). Senecio serratuloides extract prevents the development of hypertension, oxidative stress and dyslipidemia in nitric oxide-deficient rats. Journal of Complementary and Integrative Medicine, 17(2).
- Gondwe, M. M., Mpungose, A., Kamadyaapa, D. R., Shauli, M., Ndebia, E., Sewani-Rusike, C., ... & Oyedeji, A. (2019). The protective effect of aqueous extract of Typha capensis rhizomes on cadmium-induced infertility in rats. Journal of basic and clinical physiology and pharmacology, 30(3), 201801
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