Adam Sparrow

Adam Sparrow

Research Scientist

St George’s University of London (SGUL), United Kingdom (UK)

Email: adamjamessparrow@gmail.com

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords:

TB, In vitro Work, Vaccines, Immunotherapeutics, Antibiotics

 

Biography:

I’m interested in the development of vaccines, antibiotics and immunotherapeutics which can be used against TB.  I finished my PhD in Immunology and my MRes in Biomedical Sciences at St Georges, University of London. I graduated from the University of Surrey with a Bsc in Medical Microbiology. For my PhD, I tested novel TB vaccines using in vitro models. I have also worked on developing a novel immunotherapeutic against TB and on better understanding the immune responses generated by the BCG vaccine.

 

Related Websites:

LinkedIn

 

Key Publications:

  • Munshi T, Sparrow A, Wren BW, Reljic R, Willcocks SJ. The Antimicrobial Peptide, Bactenecin 5, Supports Cell-Mediated but Not Humoral Immunity in the Context of a Mycobacterial Antigen Vaccine Model. Antibiotics (Basel). 2020 Dec 19;9(12):926. 
  • Copland, A., Sparrow, A., Hart, P. et al. Bacillus Calmette-Guérin Induces PD-L1 Expression on Antigen-Presenting Cells via Autocrine and Paracrine Interleukin-STAT3 Circuits. Sci Rep 9, 3655 (2019).
  • Diogo GR, Sparrow A, Paul MJ, Copland A, Hart PJ, Stelter S, van Dolleweerd C, Drake PMW, Macallan DC, Reljic R. Murine IL-4Δ2 splice variant down-regulates IL-4 activities independently of IL-4Rα binding and STAT-6 phosphorylation. Cytokine. 2017 Nov;99:154-162.