Alba Llibre Serradell

Alba Llibre Serradell

Assistant Professor

University of Birmingham, United Kingdom (UK)

Email: a.llibre@bham.ac.uk

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords: 

Tuberculosis, Cytokine Responses, Immunometabolism

 

Biography:

Dr Llibre grew up in Barcelona, where she did her BA in Biotechnology. She pursued a MSc in Virology at Imperial College London and a PhD in Human Immunology at the University of Oxford. She continued studying host immune responses in infectious diseases at the Institut Pasteur in Paris, where she focused on understanding functional immune responses to Mycobacterium tuberculosis. She joined the University of Birmingham (UoB) in March 2020, funded by a Marie Skłodowska-Curie Fellowship, to investigate host immune and metabolic responses in the context of tuberculosis. She was appointed Assistant Professor at UoB in April 2023.

 

Related Websites: 

University of Birmingham - Staff Profile

 

Key Publications:

  • Rodrigues KB*, Dufort MJ*, Llibre A, Speake C, Rahman J, Bondet V, Quiel J, Linsley PS, Greenbaum CJ, Duffy D, Tarbell KV. Innate immune stimulation of whole blood reveals type 1 IFN hyper-responsiveness in type 1 diabetes. Diabetologia 2020. (Accepted).
  • Llibre A, Bilek N, Bondet V, Darboe F, Mbandi SK, Penn-Nicholosn A, Hatherill M, Rozenburg F, Scriba TJ, Duffy D. Plasma type I IFN protein concentrations in human tuberculosis. Front Cell Infect Microbiol 2019. doi: 10.3389/fcimb.2019.00296.
  • Duffy D, Nemes E, Llibre A, Rouilly V, Filander E, Africa H, Mabwe S, Jaxa J, Charbit B, Musvosvi M, Mulenga H, the Milieu Intérieur Consortium, Thomas S, Hatherill M, Bilek N, Scriba TJ, Albert ML. Immune profiling in M. tuberculosis infection enables stratification of patients with active disease. BioRxiv 2019. https://www.biorxiv.org/content/10.1101/581298v1
  • GI Rice, C Meyzer, N Bouazza, M Hully, N Boddaert, M Semarero, LAH Zeef, F Rozenberg, V Bondet, D Duffy, A Llibre, J Baek, MN Sambe, E Henry, V Jolaine, C Barnerias, M Barth, A Belot, C Cances, G Debray, D Doummar, ML Frémond, N Kitabayashi, A Lepelley, V Levrat, I Melki, P Meyer, MC Nougues, F Renaldo, M Rodero, D Rodriguez, A Roubertie, L Seabra, C Uggenti, H Abdoul, JM Treluyer, I Desguerre, SBlanche, YJ Crow. Reverse transcriptase inhibitors in Aicardi-Goutières syndrome. N Engl J Med 2018. doi: 10.1056/NEJMc1810983.
  • Llibre A, Shimakawa Y, Duffy D. Potential utility of the Genedrive point-of-care test for HCV RNA detection. Gut 2018. doi: 10.1136/gutjnl-2018-317218.
  • Llibre A, Duffy D. Immune response biomarkers in human and veterinary research. Comp Immunol Microbiol Infect Dis 2018. doi: 10.1016/j.cimid.2018.09.008.
  • Llibre A*, Bondet V*, Rodero MP, Hunt D, Crow Y, Duffy D. Development and validation of an ultrasensitive single molecule array digital ELISA for human IFNα. J Vis Exp. 2018. IF: 1.12. doi: 10.3791/57421.
  • Llibre A*, Shimakawa Y*, Mottez E, Ainswroth S, Buivan TP, Firth R, Harrison E, Rosenberg AR, Meritet JF, Fontanet A, Castan P, Madejon A, Laverick M, Pol S, McClure P, Irving W, Miele G, Albert ML, Duffy D. Development and clinical validation of the Genedrive point-of-care test for qualitative detection of Hepatitis C virus. Gut 2018. doi: 10.1136/gutjnl-2017-315783.
  • Musvosvi M, Duffy D, Filander E, Hadn A, Mabwe S, Nkantsu L, Bilek N, Llibre A, Rouilly V, Hatherill M, Albert M, Scriba T, Nemes E. T cell biomarkers for diagnosis of tuberculosis: candidate evaluation by a simple whole blood assay for clinical translation. Eur Respir J 2018. doi: 10.1183/13993003.00153-2018.
  • Llibre A, Garner L, Partridge A, Freeman G, Klenerman P and Willberg CB. Expression of Lectin-Like Transcript-1 in human tissues.  F1000Research 2016. doi: 10.12688/f1000research.10009.1
  • Llibre A, Klenerman P and Willberg CB. Multi-functional Lectin-Like Transcript-1: a new player in immune regulation. Immunol Lett 2016. doi: 10.1016/j.imlet.2016.07.007.
  • Llibre A, Lopez-Macias C, Marafioti T, Mehta H, Partridge A, Kanzig C, Rivellese F, Galson JD, Walker LJ, Milne P, Phillips RE, Kelly DF, Freeman GJ, El Shikh ME, Klenerman P and Willberg CB. LLT1 and CD161 expression in human germinal centers promotes B cell activation and CXCR4 downregulation. J Immunol 2016. doi: 10.4049/jimmunol.1502462.
  • Fergusson JR, Huhn M, Swadling L, Walker L, Kurioka A, Llibre A, Newell EW, Davis MM, Bertoletti A, Hollander G, Sverremark E, Powrie F, Capone S, Folgori A, Barnes E, Willberg CB, Ussher J, Klenerman P. CD161int CD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut. Mucosal Immunol. 2015. doi: 10.1038/mi.2015.69.