Basha Chekesa Lemi

Basha Chekesa Lemi

Addis Ababa University & Wollega University, Ethiopia

Email: basha.chekesa@aau.edu.et

 

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords:

Tuberculosis and other Human Infectious Diseases’ (OMICS, EPIOMICS, Vaccinology, immunological studies, Bioinformatics, and related fields).

 

Biography:

My name is Basha Chekesa Lemi. I earned a BSc in Applied Biology from Arbamich University in 2010, an MSc in Applied Microbiology from Addis Ababa University in 2012, and a PhD in Tropical and Infectious Diseases from Addis Ababa University in 2024. My doctoral research focused on the molecular epidemiology, pangenome, and genomic signatures of Mycobacterium tuberculosis, equipping me with the skills to address complex questions in tuberculosis and related fields.

My research experience includes university teaching, and I possess skills in a diverse range of techniques. These techniques include ELISA, bacterial culture, cell culture, DNA extraction, library preparation, PCR, whole-genome sequencing, and various bioinformatics methodologies. These methodologies encompass genome quality checks, assembly, annotation, variant calling, comparative genomics, pangenome analysis, genome-wide association studies, reverse vaccinology, and simulation. Additionally, I am proficient in various bioinformatics tools, statistical software (such as R), Linux, and data visualization web servers.  I gained these experiences through my academic journey, hands-on training at the J. Craig Venter Institute, United States of America, and various other training programs.

My research interests lie in Tuberculosis and other human Infectious Diseases’ OMICS, EPIOMICS, Vaccinology, Immunological studies, Bioinformatics, and related fields. I am open-minded and looking to collaborate with anyone interested in the above research questions and other related areas.

 

Related Websites:

LinkedIn

 

Key Publications:

  • Basha Chekesa, Harinder Singh, Norberto Gonzalez-Juarbe, Sanjay Vashee, Rosana Wiscovitch-Russo, Christopher L. Dupont, Musse Girma, Oudessa Kerro, Balako Gumi, Gobena Ameni (2024). Whole-genome sequencing-based genetic diversity, transmission dynamics, and drug-resistant mutations in Mycobacterium tuberculosis isolated from extrapulmonary tuberculosis patients in western Ethiopia. Frontiers in Public Health (Accepted).
  • Basha Chekesa, Harinder Singh, Norberto Gonzalez-Juarbe, Sanjay Vashee, Rosana Wiscovitch-Russo, Christopher L. Dupont, Musse Girma, Oudessa Kerro, Balako Gumi, Gobena Ameni (2024). Pan-genome and genomic signatures linked to the dominance of the lineage-4 of Mycobacterium tuberculosis isolated from extrapulmonary tuberculosis patients in western Ethiopia: A genome-wide association study.  PLOS ONE, 10.1371/journal.pone.0304060 (Accepted)
  • Chekesa, B., Gumi, B., Chanyalew, M., Zewude, A., & Ameni, G. (2020). Prevalence of latent tuberculosis infection and associated risk factors in prison in East Wollega Zone of western Ethiopia. PLOS ONE, 15(5), e0233314. doi: 10.1371/journal.pone.0233314. 
  • Basha Chekesa and Yelamtsehay Mekonnen (2015). Antibacterial Activity of Moringastenopetala against Some Human Pathogenic Bacterial Strains. Sci. Technol. Arts Res. J. 4(2): 190-198.