Constanza Martínez-Olivares

Constanza Martinez-Olivares

Research Collaborator

Salvador Zubirán National Institute of Health Sciences and Nutrition, Mexico

Email: constanzamtz@exalumno.unam.mx

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords:

TB, Animal Models, Clinical Trials

 

Biography:

Dr. Constanza, a biotechnologist with a Ph.D. in Biochemical Sciences, specializes in the development of vaccines and therapeutic antibodies for infectious diseases, including tuberculosis and SARS-CoV-2. Her experience encompasses the design and evaluation of recombinant proteins, subunit vaccines, and monoclonal antibodies, as well as the rational design of vaccines using bioinformatics and molecular modelling, recombinant protein production, and bioprocess optimization. Her research focuses on immunotherapy and subunit vaccine strategies to improve disease prevention and treatment, with a particular emphasis on understanding host-pathogen interactions, identifying protective antigens, and applying advanced technologies in structural vaccinology and antibody engineering for innovative immunotherapeutic solutions.

 

Related Websites:

ResearchGate

 

Key Publications:

  • Valdez-Cruz, N.A., Rosiles-Becerril, D., Martínez-Olivares, C.E. et al. (2024). Oral administration of a recombinant modified RBD antigen of SARS-CoV-2 as a possible immunostimulant for the care of COVID-19. Microb Cell Fact. https://doi.org/10.1186/s12934-024-02320-5
  • Sánchez-Gloria, J.L., Martínez-Olivares, C.E., Del Valle-Mondragón. et al. (2023). Allicin, an Emerging Treatment for Pulmonary Arterial Hypertension: An Experimental Study. Int. J. Mol. Sci. 24, 12959. https://doi.org/10.3390/ijms241612959
  • Martinez-Olivares, C. E., Hernández-Pando, R., & Mixcoha, E. (2023). In silico EsxG EsxH rational epitope selection: Candidate epitopes for vaccine design against pulmonary tuberculosis. PloS one, 18(4), e0284264.https://doi.org/10.1371/journal.pone.0284264.
  • Sánchez-Gloria, J.L., Martínez-Olivares, C.E., Rojas-Morales, P. et al. (2021). Anti- Inflammatory Effect of Allicin Associated with Fibrosis in Pulmonary Arterial Hypertension. Int. J. Mol. Sci. 22, 8600. https://doi.org/10.3390/ijms22168600