Cris Vilaplana Massaguer

Head of the Experimental Tuberculosis Unit

Fundació Institut Germans Trias I Pujol (IGTP), Spain

Tel: +34930330527

Email: cvilaplana@igtp.cat

VALIDATE Role:

Network Investigator

Research Keywords:

TB, clinical trials, prognosis, biomarkers, clinical management, vaccines

Biography:

My research interests are: 1) the correlates to clinical severity and treatment response and 2) the stratification of patients to better treat them. I work on Projects studying prognostic biomarkers; developing and evaluating tools and strategies to improve the clinical management of patients (including drug and vaccine candidates), and studying the health dimensions and patients’ quality of life in the context of infectious diseases.

Key Publications:

The role of antibodies in tuberculosis diagnosis, prophylaxis and therapy: a review from the ESGMYC study group. Solomon. Tibebu Melkie, Lilibeth Arias, Chiara Farroni, Mateja Jankovic. Makek, Delia Goletti, Cristina Vilaplana. European Respiratory Review Mar.2022, 31 (163) 210218; DOI: 10.1183/16000617.0218-2021.
Impact of adjuvant therapeutic surgery on the health-related quality of life of pulmonary tuberculosis patients. Pau Benito, Sergo Vashakidze, Shota Gogishvili, Keti Nikolaishvili, Albert Despuig, Nestan T ukvadze, Natalia Shubladze, Zaza Avaliani, Cristina Vilaplana. ERJ Open Research Jul 2020, 6 (3) 00083-2020; DOI: 10.1183/23120541.00083-2020
Pujol-Cruells A and Vilaplana C (2019) Specific Interventions for Implementing a PatientCentered Approach to TB Care in Low-Incidence Cities. Front. Med. 6:273. doi: 10.3389/fmed.2019.00273
Kroesen VM, Gröschel MI, Martinson N, Zumla A, Maeurer M, van der Werf TS and Vilaplana C (2017) Non-Steroidal Anti-inflammatory Drugs As Host-Directed Therapy for Tuberculosis: A Systematic Review. Frontiers Immunol. 8:772. June 2017 doi: 10.3389/fimmu.2017.00772
Ibuprofen is able to reduce the lung pathology, to decrease bacillary load in tissues and to increase survival in a new murine experimental model of active tuberculosis. Cristina Vilaplana; Elena Marzo; Gustavo Tapia; Jorge Diaz; Vanesa Garcia; Pere-Joan Cardona. J Infect Dis. 2013 Jul 15;208(2):199-202. doi: 10.1093/infdis/jit152. Epub 2013 Apr 5

Weblinks of Interests: