PhD student
Stellenbosch University, South Africa
Email: francisaduhigh@gmail.com
VALIDATE Role:
Network Affiliate
Research Keywords:
Cancer Biology, Cell Biology, Tuberculosis, Antimicrobial Resistance.
Biography:
In my current research, I am diving deep into exploring the anticancer potential of a natural compound derived from Cape fynbos, a unique ecosystem in South Africa. Specifically, I'm investigating its effectiveness against Triple Negative Breast Cancer (TNBC), a particularly aggressive and challenging subtype of breast cancer. My focus is on unravelling the intricate workings of cancer cells at the mitochondrial level, aiming to understand how this natural compound impacts their bioenergetics. By examining the mitochondrial processes within cancer cells, I hope to gain insights into how this compound interferes with their growth and survival mechanisms. Additionally, I'm employing advanced RNA sequencing techniques (RNAseq transcriptomics) to identify specific genes that are either overexpressed or under-expressed in response to the treatment. This holistic approach allows me to uncover potential molecular targets and pathways that could be exploited for the development of more effective TNBC therapies. Overall, my research endeavours aim to harness the power of nature and cutting-edge molecular biology techniques to combat TNBC and improve patient outcomes.
Key Publications:
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