Mathulo Mathabiso Shauli

Mathulo Mathabiso Shauli

Lecturer

Walter Sisulu University, South Africa

Email: mshauli@wsu.ac.za

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords:

TB, Animal Models, Cell Culture Systems, Natural Products, Medicinal Plants

 

Biography:

My research interest is investigating natural product (medicinal plants) testing their potential to immunomodulate the key cells (macrophages) that get infected by Mycobacterium tuberculosis. I test the ability of cells to resist manipulations by the bacteria, where the cell switches to a phenotype (M2) that is ineffective in the degradation and destruction of the bacterium. Medicinal plants tested have displayed sound immunomodulatory effects on these cells, where I observed the switching from M0 to M1 phenotype, which can destroy the bacteria through the intracellular nitric oxide pathway.

 

Related Websites:

LinkedIn

 

Key Publications:

Google Scholar