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Postdoctoral Researcher
University of Cape Town (UCT), South Africa
Email: rudranil.hazra@uct.ac.za
VALIDATE Role:
Network Associate
Research Keywords:
Tuberculosis, B Cell Immunology, Macrophage Metabolism, Immune Synapse
Biography:
My research field focuses on the evaluation of recombinant BCG vaccines to target unique immune B cell population in order to improve tuberculosis (TB) control as well as to assess their robustness towards host/pathogen genetics, drug resistance, and effects of these strains when restimulating Peripheral blood cells from TB and TB/HIV patients before, during and after therapy.
Related Websites:
LinkedIn Profile
Key Publications:
- Sen P, Ghosal S, Hazra R, Arega S, Mohanty R, Kulkarni KK, Budhwar R and Ganguly N (2019). "Transcriptomic Analyses of Gene Expression by CRISPR Knockout of miR-214 in Cervical Cancer Cells." Genomics 112, no. 2: 1490-99.
- Sen P, Ghosal S, Hazra R, Mohanty R, Arega S, Sahu B and Ganguly N (2020). "CRISPR-Mediated Knockdown of miR-214 Modulates Cell Fate in Response to Anti-Cancer Drugs in HPV negative and HPV positive Cervical Cancer Cells." J Biosci 45.
- Ozturk M, Chia JE, Hazra R, Saqib M, Maine RA, Guler R, Suzuki H, Mishra BB, Brombacher F and Parihar SP (2021) “Evaluation of Berberine as an Adjunct to TB treatment.” Front. Immunol. 12:656419.
- Jones S, Ozturk M, Kieswetter NS, Poswayo S, Hazra R, Tamgue O, Parihar SP, Suzuki H, Brombacher F and Guler R (2022) “Lyl-1-deficiency promotes inflammatory response and increases mycobacterial burden in response to Mycobacterium tuberculosis infection in mice.” Front Immunol. 13:948047.
- Savulescu A, Peton N, Oosthuizen D, Hazra R, Rousseau R, Mhlanga M and Coussens AK (2023) “Mycobacterium tuberculosis infection of primary human monocyte-derived macrophages on microfabricated patterns.” Cell Reports Methods. Volume 3, Issue 11, 100640.
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