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Researcher
Armauer Hansen Research Institute (AHRI), Ethiopia
Email: sebsibneway2152@gmail.com
VALIDATE Role:
Network Affiliate
Research Keywords:
TB, TB MDR, MTB, Other Bacterial Disease
Biography:
My name is Sebsib Neway. I have an MSc in Microbiology from Addis Ababa University and a BSc in Medical Laboratory Technology from Haramaya University. I am currently working as a researcher at Armauer Hansen Research Institute (AHRI) where I am mainly working on diagnostics, pathogenesis and drug resistance of tuberculosis (TB). Over the years, I have acquired extensive expertise in molecular and immunological aspects of tuberculosis, with a particular interest in smear-negative tuberculosis, non-tuberculosis mycobacteria and drug susceptibility testing. My research is also focussed on new diagnostic approaches such as saliva-based PCR tests and T-cell reaction profiling in TB patients.
To date, I have contributed to over 18 publications, with several studies under editorial review. Notable work includes studies on dual-functional CD4+ T cells in smear-negative TB, genetic diversity and resistance patterns of M. tuberculosis, and determinants of culture conversion in time in MDR-TB patients. I have also published studies on more general topics related to infectious diseases, e.g. infections after caesarean section, external bacterial infections of the eye and antimicrobial resistance in the clinical setting. My overall goal is to advance evidence-based strategies for tuberculosis diagnosis and control, especially in resource-limited settings such as Ethiopia.
Key Publications:
- Activation and proliferation profiles of M. tuberculosis specific dual functional CD4+T cells from smear negative pulmonary TB patients (accepted under editorial).
- Post-Caesarean Section Infection Burden, Antimicrobial Resistance Pattern, and Associated Factors at All Africa Leprosy Rehabilitation and Training Center Comprehensive Specialized Hospital, Addis Ababa, Ethiopia (accepted under editorial).
- Detection of Mycobacterium tuberculosis in Saliva by Real-Time PCR: A Potential Method for Enhancing Tuberculosis Diagnosis.
- Phenotypic and genotypic drug susceptibility patterns of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Central and Southern Ethiopia.
- Determinants of Sputum Culture Conversion Time in Multidrug-Resistant Tuberculosis Patients in ALERT Comprehensive Specialized Hospital, Addis Ababa, Ethiopia: A Retrospective Cohort Study. 2024
- Clinical and Imaging Characteristics of Smear Negative Pulmonary Tuberculosis Patients: A Comparative Study. 2023
- Genetic Diversity and Drug Resistance Pattern of Mycobacterium tuberculosis isolates among Sputum Smear Negative Tuberculosis Patients in Addis Ababa. 2023
- Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients. 2023
- A glimpse into the genotype and clinical importance of non-tuberculosis mycobacteria among pulmonary tuberculosis patients: the case of Ethiopia.
- Mycobacterium tuberculosis antigen-specific T cell responses in smear positive and -negative pulmonary tuberculosis patients
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