Weekly round-up #246
Watch today - VALIDATE Workshop - NIH101: A Guide to Applying for National Institutes of Health Funding
49 VALIDATE members gathered on Zoom to hear Dr Katrin Eichelberg provide invaluable advice on finding funding from the US's National Institutes of Health and tips on putting together an application.
Watch online - The event was recorded and is available to VALIDATE members who have signed our CDA. If you wish to watch the video, you can request access by emailing VALIDATE@ndm.ox.ac.uk.
Next week - Targeting Immunometabolism in Host Defense Against Mycobacterium Tuberculosis with Dr Luciana Balboa
14 December - 15:00 GMT
In this seminar, Dr Balboa will discuss how her team focused on unravelling the immunometabolic pathways that regulates leucocytes’ functions and their impact on the control of TB. To study the impact of TB-associated microenvironment on the functionality of M1 macrophages, they used the acellular fraction of pleural effusions from TB patients (TB-PE). Interestingly, they found that M1 macrophages exposed to TB-PE displayed a lower expression of HIF-1α and a reduced glycolytic activity, impairing the control of bacterial growth.
Find out more and Register - www.validate-network.org/event/immunometabolism-host-defense-mtb
- NIH Complement in Basic Immunology CIBI - Supports studies that accelerate our understanding of the roles of complement components and/or receptors in the initiation, magnitude, maintenance, and quality of immune responses against infectious agents - deadline: 8 January 2023
- UKRI Policy Fellowships - Funding to collaborate on research activity to address pressing national and global challenges - deadline TBA (April 2023)
- NIH Cooperative Centers on Human Immunology - Supports mechanistic and hypothesis-testing studies to discover novel molecules, mechanisms, or regulatory pathways governing function of the human immune system in both healthy and vulnerable populations - deadline 7 April 2023
You can find a list of all relevant external funding we've spotted for our members on our external funding page.
Training Opportunities and Events:
- Asset Africa: How to Write a Winning Proposal, Online course over 8 weeks, starts 17 December 2022
- International Conference on Infectious Diseases 2023, Hotel Isola Sacra Rome Airport, Rome, Italy, 20 - 21 March 2023
Find more event opportunities on our Training and Events pages.
-
Postdoctoral Fellowship in Tuberculosis Immunology, South African Tuberculosis Vaccine Initiative (SATVI), University of Cape Town, deadline 15 December 2022
Other relevant career opportunities are on our jobs page.
- Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis, Karmakar S et al, in NPJ Vaccines
- Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis, Jeyanathan M et al, in Nature Immunology
- Mycobacterium tuberculosis-specific CD4 T cells expressing transcription factors associate with bacterial control in granulomas, L. Grant NL et al, in bioRxiv
Check out our Publications Page for members' publications and email VALIDATE@ndm.ox.ac.uk if you have a paper you would like us to include.
Highlights on Twitter this week:
The Daily Maverick (South Africa) reported that lessons from COVID-19 are essential in developing a response to TB, Nature released a new resource for researchers, and former head of the Anthony Fauci stated that responding to non-COVID pathogens like TB is crucial. Pharma time reported on a clinical trial taking place in Germany for the VPM1002 vaccine for TB and Prof Susie Dunachie celebrated fellow VALIDATE member Aparna Dravid passing a one-month training course at Oxford. Nature careers had advice for young scientists about protecting research ideas and talked about a network for mothers in science.
Keep up to date with all the relevant news and opportunities by following @NetworkVALIDATE on Twitter.
Published: 6 December 2022
