Seattle Children’s Hospital - Research Scientist IV, 2020
Deadline for applications: 1 May 2020
About Us
Hope. Care. Cure. These three simple words capture what we do at Seattle Children’s – to help every child live the healthiest and most fulfilling life possible. Are you ready to engage with a mission-driven organization that is life-changing to many, and touches the hearts of all? #HOPECARECURE
As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care, and cures to help every child live the healthiest and most fulfilling life possible.
Our investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine.
Researchers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report’s top children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.
We are committed to not only treating disease but to eliminating it. Help us achieve our vision of being a worldwide leader in pediatric research aimed to improve the health and well-being of children. If you are interested in a challenging career aimed at groundbreaking research, Seattle Children's Research Institute is the place for you.
Overview
A scientist position is available in the Clinical Immunology Group. The successful candidate will be involved in characterizing functionality of immune cells. Previous experience in human immunology and cellular immunoassay, including multiparametric flow cytometry, is a must. Excellent organizational and communication skills are required.
Primary Responsibilities:
• Oversee clinical immunology group and assessment of immunological endpoints in vaccine clinical trials including assay development and validation.
• Contribute to study designs, clinical study reports, statistical analysis plans, manuscripts, and grant applications.
• Oversee and perform specimen processing, training, and shipping for domestic and international sites.
• Design and execute research projects that further the understanding and development of effective vaccines.
• Responsible for experimental design and developing immunoassay methodology following scientific
literature review, quality standards and discussion with peers, as required.
• Responsible for preparing Standard Operating Procedures and development/optimization/ qualification/validation reports for immunoassays.development and implementation.
• Participate in laboratory audits to ensure GCLP-like compliance and assist with clinical training activities.
• Records procedures, outcomes and observations in lab notebook following established guidelines.
• Utilize established mathematical and scientific techniques to compile and critically analyze and interpret
data.
• Communicate with research management on a regular basis.
• Prepare manuscripts for publication in peer reviewed journals.
• Presents research at group and internal/external scientific meetings.
• Participate in grant writing.
• Supervision of research assistant(s) and/or associate(s).
Requirements
Required Education/Experience:
• A PhD in immunology or related discipline and a minimum of 3 years of related postdoctoral research
experience.
• Experience in microbiology and/or infectious diseases.
• Minimum of four (4) years experience in required field of specialization
• Experience and skills with PBMC processing, humoral, and/or cellular immunology and human T- and B-cell based functional assays (e.g., flow cytometry, ELISPOT, CTL, ELISA and Luminex).
• Experience in one or more of the following areas: clinical trials, project management, assay development, assay validation, generating budgets for laboratory procedures, training clinical sites on specimen processing (domestic and international), repository management, management of research associates
• A strong track record of publication.
• Experience working under Biosafety Level 2 or 3 (BL2/BL3) conditions.
• Excellent oral and written communication skills in English.
• Proficiency in MS Office, scientific data/graphics programs, and biostatistics.
• Must be self-motivated, highly organized and be able to work on teams.
For more information, or to apply, visit the job webpage.
