The VALIDATE Network - Vaccine development for complex intracellular neglected pathogens
Senior Laboratory Research Scientist (TB), Francis Crick Institute, UK, Aug 2018
Senior Laboratory Research Scientist (TB)
Employer: Francis Crick Institute, London, UK
Fixed-term for 4 years
An exciting opportunity to be part of a pioneering biomedical research institute, dedicated to innovation and science. A Senior Laboratory Research Scientist post in the laboratory of Max Gutierrez is now available. This role will be pivotal in ensuring research activities in containment 2 and 3 levels for the research group “Host-pathogen interactions in tuberculosis”. This role is critical to generate tools and perform experiments in CL2/CL3 labs as well as training of new people joining the group. This role requires substantial experience in mycobacterial genetics and/or stem cell culture/CRISPR/Cas9 targeting. Experience in imaging and image analysis is desirable. This role reports to Max Gutierrez.
Our group is interested in the area of cellular microbiology of M. tuberculosis with a focus on the innate immune system and phagocytosis. In particular, we are interested in understanding how M. tuberculosis survive within host cells and the mechanisms that host cells use to eliminate intracellular M. tuberculosis.
The position has been created to ensure the successful implementation of a research project funded by the European Research Council (ERC) that aims to develop imaging tools to better understand the complex interactions between M. tuberculosis and human macrophages.
About The Francis Crick Institute
The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.
An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King’s College London.
The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.
The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.