Yasaman Taslimi

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Yasaman Taslimi

Researcher

Pasteur Institute of Iran, Iran

Email: ytaslimi@yahoo.com

 

 

 

 

VALIDATE Role:

Network Associate

 

Research Keywords:

Leishmaniasis

 

Biography:

Since 2000, I have been working in the Immunotherapy and Leishmania Vaccine Research Department at the Pasteur Institute of Iran. During my 24 years of experience, I have contributed to diverse research projects that have encompassed diagnostic methods, the design of DNA and live vaccines against leishmaniasis, and the evaluation of drug efficacy.

My M.Sc. research focused on the use of Leishmania tarentolae as a live therapy to deliver IP-10 (Interferon gamma inducible protein 10) to a mice model of breast cancer. Our research revealed that non-pathogenic live vaccines may be a potent and efficacious strategy for vaccination, particularly for different types of leishmaniasis. I am delighted to share my research findings and expertise with other VALIDATE members.

In recent years, my focus has been on non-invasive sampling and point-of-care diagnosis techniques for cutaneous leishmaniasis (CL). CL primarily impacts underprivileged populations in developing countries that have limited access to financial and healthcare resources. Our objective is to facilitate rapid, painless, and safe diagnosis of the disease using the current non-invasive technique, particularly for children and patients with lesions in sensitive areas of their body, such as the face.

We are enthusiastic about disseminating the methodology to all research or medical centres grappling with CL diagnosis challenges.

 

Key Publications:

  • Yasaman Taslimi , Sima Habibzadeh , Vahid Mashayekhi Goyonlo , Amin Akbarzadeh, Zahra Azarpour, Safoora Gharibzadeh, Mehrdad Shokouhy, Josefine Persson, Ali M. Harandi *, Amir Mizbani *, Sima Rafati* Tape-disc-loop-mediated isothermal amplification (TD-LAMP) method as noninvasive approach for diagnosis of cutaneous leishmaniasis caused by L. tropica. Heliyon. Volume 9, Issue 11, November 2023, e21397.
  • Yasaman Taslimi, Christopher Agbajogu, Siggeir Fannar Brynjolfsson, Nasrin Masoudzadeh,Vahid Mashayekhi, Safoora Gharibzadeh, Malin Östensson, Sravya Sowdamini Nakka, Amir Mizbani, Sima Rafati1, Ali M. Harandi. Profiling Inflammatory Response in Lesions of Cutaneous Leishmaniasis Patients Using a Non-Invasive Sampling Method Combined With a High-Throughput Protein Detection Assay.Cytokine.2020 Mar 17;130:155056.doi: 10.1016
  • Taslimi Y, Sadeghipour P, Habibzadeh S, Mashayekhi V, Mortazavi H, Müller I, Lane ME, Kropf P, Rafati S. A novel non-invasive diagnostic sampling technique for cutaneous leishmaniasis. PLoS Negl Trop Dis. 2017 Jul 13;11(7).
  • Taslimi Y, Zahedifard F, Rafati S. Leishmaniasis and various immunotherapeutic approaches, Parasitology, Accept 29, October, 2016.
  • Yasaman TASLIMI, Farnaz ZAHEDIFARD, Tahereh TAHERI, Delaram DOROUD, Sakineh LATIF DIZAJI, Noushin SALJOUGHIAN, and Sima RAFATI. Comparison of Protective potency of DNA and Live vaccines expressing parasite ‎antigens against visceral leishmaniasis in hamster Syrian as preliminary study. Iranian Journal of Parasitology, Accept November 2016
  • Taslimi Y, Zahedifard F, Habibzadeh S, Taheri T, Abbaspour H, Sadeghipour A, Mohit E. Rafati S. Antitumor Effect of IP-10 by Using Two Different Approaches: Live Delivery System and  Gene Therapy, J Breast Cancer 2016 March; 19(1): 34-44.