Adrian Wildfire

Adrian Wildfire


CHIMagents, UK

Tel: +44 (0)7770 862571






Network Associate


Research Keywords: 

CHIM, URTIs (influenza / RSV), the hepatides



Researching the links between infectious pathogens and their mechanisms of disease promotion e.g. immune downregulation, especially where related to the interventional potential of novel drugs and vaccines. Adrian also has a special interest and expertise in modelling such relationships in challenging environments e.g. influenza, RSV, malaria, and others.


Related Websites: 


Key Publications:

  • Modelling the World - can deliberately infecting healthy volunteers really tell us much about what happens outside the clinic during an epidemic or pandemic? Wildfire, A. Drug Discov Today. 2021; 26(3):617-619. PMCID: PMC7800137, PMID: 33444789. doi:10.1016/j.drudis.2020.11.035
  • Human challenge trials in vaccine development. Baay MFD, Richie TL, Neels P, Cavaleri M, Chilengi R, Diemert D, Hoffman SL, Johnson R, Kirkpatrick BD, Knezevic I, Laurens M, McShane H, Njuguna P, Older Aguilar A, Pollard AJ, Riddle M, Sauerwein R, Southern J, Tribble D, Wildfire A.  Biologicals. 2018 Mar 21. pii: S1045 – 1056 (18) 30039-3. doi: 10.1016/j.biologicals.2018.02.002             
  • Human challenge trial workshop: Focus on quality requirements for challenge agents. Bekeredjian-Ding, I. Van Molle, W. Baay, M. Neels, P. PEI speakers and session chairs. Langen, Germany, October 22, 2019. Biologicals. 2020 Jul;66:53-61. doi: 10.1016/j.biologicals.2020.04.005. Epub 2020 May 4. PMID: 32389512