Gladys Granero

Gladys Granero


University National of Córdoba

Tel: +54-351-5730811






Network Investigator


I am Full Associate Professor and Principal Researched of the National Council for Scientific and Technical Research (CONICET) from the University National of Córdoba (Argentina). My research interest lies in the area of Nanotechnology, particularly focusing on Tuberculosis infection. In recent years my research projects include the development of new nanoparticulate delivery systems to combat antibiotic resistance, with a special focus on Tuberculosis. Currently, I participate in an interinstitutional project for the development of nanovaccines against Tuberculosiss


Key Publications:

Alicia Delrivo, Carolina Aloisio, Marcela R. Longhi, Gladys Granero. Artificial lipid membrane permeability method for predicting intestinal drug transport: probing the determining step in the oral absorption of sulfadizaine; influence of the formation of binary and ternary complexes with cyclodextrins. AAPS PharmSciTech , 19(3), 1437-1447,  2018.

Javier Adrián Calles, Maria Julia Mora, Renée Onnnainty, Luis Ignacio Tartara, Gladys Ester Granero, Marcela Raquel Longhi, Yolanda Diebold, Enrique Marcelo Vallés, Santiago Daniel Palma. Cross-linked hyaluronan films loaded with acetazolamide-cyclodextrin-triethanolamine complexes for glaucoma treatment. Therapeutic Delivery, 9(3), 205-219,  2018.

Zelenková, T., Onnainty, R., Granero, G.E., Barresi, A.A., Fissore, D.  Use of microreactors and freeze-drying in the manufacturing process of chitosan coated PCL nanoparticles. Eur. J. Pharm. Sci., 119, 135-146, 2018.

Aloisio,C., Ponce-Ponte, M., Granero, G.E., Longhi, M.R. Effect of complexes and microemulsions on the permeability of drugs: determination using a new biomimetic artificial membrane. AAPS PharmSciTech, 19(6), 2629-2638 2018.

Zelenková, T., Onnainty, R., Granero, G.E., Barresi, A.A., Fissore, D. Use of microreactors and freeze-drying in the manufacturing process of chitosan coated PCL. Eur. J. Pharm. Sci., 119, 135-146, 2018.

1Mora, M.J., Onnainty, R., Granero, G.E. Comparative oral drug classification systems: acetazolamide, azithromycin, clopidogrel and efavirenz case studies. Mol. Pharm., 15(8), 3187-3196 2018.

Quinteros, M.A., Viviana, C.A., Onnainty, R., Mary, V.S., Theumer, M.G., Granero, G.E., Paraje, M.G., Páez, P.L. Biosynthesized silver nanoparticles: Decoding their mechanism of action in Staphylococcus aureus and Escherichia coli. Int. J. Biochem. Cell Biology 104, 87-93, 2018.

Scolari, I.R., Páez, P.L., Sánchez-Borzone, M.E., Granero, G.E. Promising Chitosan-Coated Alginate-Tween 80 Nanoparticles as Rifampicin Coadministered Ascorbic Acid Delivery Carrier Against Mycobacterium tuberculosis. AAPS PharmSciTech 20(2), 67, 2019.45.      

Scolari, I.R., Páez, P.L., Musri, M.M., Petiti, J.P., Torres, A. Granero, G.E. Rifampicin loaded in alginate/chitosan nanoparticles as a promising pulmonary carrier against Staphylococcus aureus. Drug Delivery and Translational Research. 2020, 10(5), 1403-1417.46.

Scolari, I.R., Volpini, X., Fanani, M.L., ...Musri, M.M., Granero, G.E. Exploring the toxicity, lung distribution, and cellular uptake of rifampicin and ascorbic acid-loaded alginate nanoparticles as therapeutic treatment of lung intracellular infections. Molecular Pharmaceutics, 2021 Mar 1;18(3):807-821. doi: 10.1021/acs.molpharmaceut.0c00692.

Onnainty, R., Usseglio, N., Bonafé Allende, J.C., Granero, G.E. Exploring a new free-standing polyelectrolyte (PEM) thin film as a predictive tool for drug-mucin interactions: Insights on drug transport through mucosal surfaces. International Journal of Pharmaceutics, 2021, 604,120764. DOI 10.1016/j.ijpharm.2021.120764.

Peralta, M.F., Mendieta, S.N., Scolari, I.R., Granero, G.E., Crivello, M.E. Synthesis and release behavior of layered double hydroxides–carbamazepine composites. Scientific Reports, 11(1), 20585, 2021.


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