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Professor of Microbiology
Institute Hospital Universitari “Germans Trias i Pujol”. Badalona, pain
Tel: +34 93 497 8894
Email: pcardonai.germanstrias@gencat.cat
VALIDATE Role:
Network Investigator
Research Keywords:
TB, animal models, clinical trials, coevolution, vaccines, chemotherapy
Biography: I’m studying TB from an immunopathogenic point of view, using several experimental modelling “in vitro”, “in vivo” and “in silico”, and leading several clinical trials. Inventor of RUTI immunotherapy against TB and worked in Mycolicibacterium immunomodulation properties. Nowadays also interested in host-pathogen co-evolution. I love to interact and letting grow new ideas and concepts.
Key Publications:
- Russell DG., Cardona PJ., Kim MJ., Allain S., Altare, F. Foamy macrophages and the progression of the human tuberculosis granuloma. Nat Immunol 2009; 10, 943-948. doi: 10.1038/ni.1781
- Cardona, PJ. A dynamic reinfection hypothesis of latent tuberculosis infection. Infection. 2009; 37 (2): 80-86. doi: 10.1007/s15010-008-8087-y.
- Gil O., Diaz, I., Vilaplana C., Tapia G., Diaz J., Fort M., Caceres N., Pinto S., Cayla K., Corner L., Domingo M., Cardona PJ. Granuloma encapsulation is a key factor for containing tuberculosis infection in minipigs. PLOS One. 2010 Apr 6; 5(4):e10030. doi: 10.1371/journal.pone.0010030.
- Aagaard C., Hoang T., Dietrich J., Cardona PJ., Izzo A., Dolganov G., Schoolnik GK., Cassidy J., Billeskov R., Andersen P. 2011. A multistage tuberculosis vaccine that confers efficient protection pre– and post–exposure. Nat Med. 2011 Feb;17(2):189-94. Epub 2011 Jan 23. doi: 10.1038/nm.2285.
- Vilaplana C., Marzo E., Tapia G., Diaz J., Garcia V., Cardona PJ. Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis. J Infect Dis. 2013 Jul 15;208(2):199-202. doi: 10.1093/infdis/jit152.
Weblinks of Interest:
Clinical and Experimental Microbiology | Infectious Diseases | IGTP
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