Rogelio Hernandez-Pando

Chairman of Experimental Pathology Section, Department of Pathology

National Institute of Medical Sciences and Nutrition (INCMNSZ), Mexico

Email: rogelio.hernandezp@incmnsz.mx

VALIDATE Role: Investigator

Research Keywords

TB, animal models

Biography

Prof Rogelio Hernandez Pando is an MD, specialist in Pathology, PhD in Immunology from the Medicine School and Biomedical Research Institute at National University of Mexico, and postdoctoral studies at Bacteriology Department, School of Pathology University College of London UK. Since the last 15 years he has been the Chairman of the Experimental Pathology Section, Department of Pathology at National Institute of Medical Sciences and Nutrition in Mexico City., which is considered the best academic center in Medicine

Key Publications

Hernández Pando R, Orozco EH, Sampieri A, Pavón L, Velasquillo C, Larriva SJ, Madrid MV. Correlation between the kinetics of Th1/Th2 cells and pathology in a murine model of experimental pulmonary pathology. Immunology 1996; 89: 26-33.

Hernández Pando R., Orozco EH, Arriaga K, Sampieri A, Larriva SJ, Madrid MV. Analysis of the local kinetics and localization of interleukin 1 alpha, tumor necrosis factor alpha and transforming growth factor beta, during the course of experimental pulmonary tuberculosis. Immunology 1997, 90: 607-617.

Hernández Pando R, Pavón L. Arriaga K, Orozco EH, Madrid MV, Rook GAW: Pathogenesis of tuberculosis in mice exposed to low and high doses of an enviromental mycobacterial saprophyte before infection. Infect and Immun 1997; 65: (8) 3317-3327

Hernández-Pando R, Jeyanathan M, Mengistu G, Aguilar D, Orozco H, Harboe M, Rook GAW, Bjune G. Persistence of DNA from M. tuberculosis in superficially normal lung tissue during latent infection:The Lancet; 2000, 356: 2133-2138.

Arriaga AK, Orozco EH, Aguilar LD, Rook, GAW, Hernández Pando R. Immunological and pathological comparative analysis between experimental latent tuberculosis infection and progressive pulmonary tuberculosis. Clin Exp Immunol 2002; 128: 229-237.

Hernández Pando R, Aguilar LD, García HLM, Orozco EH, Rook GAW. Pulmonary tuberculosis in Balb/c mice with non-functional IL-4 genes, changes in the regulation of fibrosis and in the inflammatory effects of TNFα. European Journal of Immunology 2004, 34: 174-183.

Hernández Pando R, Aguilar León D, Orozco EH, Serrano A, Ahlem C, Trauger R, Schramm B, Reading C, Frincke J, Rook GAW. 16-alpha-bromoepiandrosterone (HE2000) restores Th1 and accelerates chemotherapy-induced bacterial clearance in a model of progressive pulmonary tuberculosis. Journal of Infectious Diseases 2005; 191: 299-306.

Mata Espinosa D, Mendoza Rodriguez V, Aguilar León D, Rosales R, López Casillas F, Hernández Pando R. Therapeutic effect of recombinant adenovirus encoding interferon gamma in a murine model of progressive pulmonary tuberculosis. Molecular Therapy 2008; 16(6): 1065-1072.

Marquina-Castillo B, García-García L, Ponce-de-León A, Jiménez-Corona ME, Bobadilla-Del Valle M, Cano-Arellano B, Canizales-Quintero S, Martínez-Gamboa A, Kato-Maeda M, Robertson B, Young D, Small P, Schoolnik G, Sifuentes-Osornio J, Hernández-Pando R. Virulence, immunopathology and transmissibility of selected strains of Mycobacterium tuberculosis in a murine model. Immunology. 2009 Sep; 128(1):123-33.