Weekly round-up #176
Some exciting news for VALIDATE. As you know, VALIDATE has been developing a series of educational computer/video games called BCG Adventures. This week marks the 100th anniversary of the first use of the BCG vaccine for humans so we are encouraging VALIDATE members to play the games and share them as widely as possible right now - www.validate-network.org/bcg-adventures
Who are the games for? - These games are for VALIDATE members, researchers and teachers who need a fun and unique resource that can engage young people with the often dry topics of immunology, vaccines and the history of science. The games are available for free and can be played either in a browser by anyone who wishes to play them. They will be both fun and informative for people of all ages but are specifically aimed at UK Key Stage 3 students (aged 11-14). The games are available online but can be downloaded and work as a useful tool for researchers who take part in science festivals and career fairs.
Play the games now!
Albert and Camille’s Little Lille Adventure is an exploration and adventure game in which you navigate characters around a map of occupied Lille in 1917. Players take the part of both Albert Calmette and Camille Guérin and interact with Lille's citizens to obtain the necessary supplies for their important vaccine research whilst avoiding soliders.
As the player collects each item, they will learn about the methods used to create BCG, and how vaccines work.
Vaccine Delivery Adventure is a classic side-scrolling action game where a healthcare worker has to overcome the challenges of delivering vaccines worldwide. Avoid local dogs, dangerous traffic and deliver the vaccine in different locations.
As the player progresses they will learn more and more about the BCG vaccine and the challenges of protecting communities against tuberculosis.
VALIDATE members get involved
- Play the game and feedback: Members can play each game and let us know what you think either by completing the feedback forms on each page or emailing us - validate@ndm.ox.ac.uk
- Spread the word: Let your friends and colleagues know and share the games widely on social media. You can find a number of screenshots, gifs and other promotional materials on the BCG Adventures Page.
- Help develop the next game: We still plan to make two additional games over the summer and we need your help. VALIDATE members can get involved and advise on the science and educational content of the game - validate@ndm.ox.ac.uk
The next VALIDATE Indusry Seminar - Tomorrow, 14:00 BST
There is still time to register for tomorrow's VALIDATE Industry Seminar. In Tuberculosis Infection and T cell-Mediated Immunity, Dr Xiao from Oxford Immunotec will be discussing the Immunology of latent TB infection (LTBI) and active TB disease, the granuloma formation and T cell medicated immunity and the immunology behind T cell-mediated immunity tests.
Spread the word and register online today - www.validate-network.org/event/immunotec
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MRC Biomedical Catalyst: Developmental Pathway Funding Scheme (DPFS) outline - Supporting the pre-clinical development and early clinical testing of novel therapeutics, devices and diagnostics, including “re-purposing” of existing therapies – 21 July 2021
- African Research Initiative for Scientific Excellence Pilot Programme - The programme is for African researchers who are African nationals with 2-7 years of research experience since completion of their PhD – 30 July 2021
- TDR Postgraduate Training Scholarship - University of the Witwatersrand - The University of the Witwatersrand’s School of Public Health invites suitably qualified candidates to apply for a full-time funded Master Degree Programme in the field of Implementation Science, 31 July 2021
- Multimodal Research Across Scales To Understand Human Disease - Apply for funding to support the development of a new research collaboration to expand understanding of human disease – 31 August 2021
- BactiVac Catalyst Training Awards - Funding is available to support training opportunities and exchanges for the transfer of knowledge and skills in bacterial vaccinology – 31 August 2021
You can find a list of all relevant external funding we've spotted for our members on our external funding page.
Training Opportunities and Events:
- BCG Centenary Symposium, Online via UCL and AHRI, 19 July 2021
- 7th European Veterinary Immunology Workshop, 2021, Online conference, 29 August 2021
- 12th Neglected Tropical Disease NGO (NNN) Conference, Online, 7 - 9 September 2021
- RSTMH Annual Meeting, Hybrid event (UK and virtual – TBC), 11 October 2021
- AREF Underserved Communities Grant Writing Workshop, Online, 11 October 2021
- TRANSVAC M12 - Requirements of GMP Production, Fraunhofer IME, Aachen Germany, 8 – 9 November 2021
- TRANSVAC M10 Assay Development and Validation, Fraunhofer IME, Aachen Germany, 10 – 11 November 2021
Find more training and events opportunities on our Training and Events pages.
- Research Assistant - Precision Vaccines Program, Boston Children's Hospital USA, deadline 31 July 2021
There are many more relevant career opportunities on our jobs page.
- The G132S Mutation Enhances the Resistance of Mycobacterium tuberculosis β-Lactamase against Sulbactam, van Alen I et al, in Biochemistry
- Epidemiology of Mycobacterium tuberculosis lineages and strain clustering within urban and peri-urban settings in Ethiopia, Taye H et al, in Plos One
- The Role of microRNAs and Long Non-Coding RNAs in the Regulation of the Immune Response to Mycobacterium tuberculosis Infection, Kundu M et al, in Frontiers in Immunology
- The effect of BCG revaccination on all-cause mortality beyond infancy: 30-year follow-up of a population-based, double-blind, randomised placebo-controlled trial in Malawi, Glynn JR et al, in The Lancet Infectious Diseases
- The role of IL-32 in Bacillus Calmette-Guérin (BCG)-induced trained immunity in infections caused by different Leishmania spp, Teodoro Silva MV et al, in Microbial Pathogenesis
Check out our Publications Page for members' publications and email VALIDATE@ndm.ox.ac.uk if you have a paper you would like us to include.
Highlights on Twitter this week:
VALIDATE Fellow Dr Rachel Tanner talked about engaging young people with Frontiers for Young Minds, we shared an article about a vaccine trial against Bovine TB and one about TB skin tests for cattle. Game developer “The Dollar Game Store” shared a test version of VALIDATE’s Little Lille Adventure computer game, BSI reminded followers about the Veterinary Vaccinology Survey, and the BBC reported on the upcoming vote on UK foreign aid. Write that PhD shared a guide to writing scientific papers for non-English speakers and Nature careers had some advice for responding to a negative peer review. We continued our #BCG100Facts with infographics on the cost of TB, UN development goals, limitations of TB antibiotics, the links between TB and HIV, the importance of a vaccine, and latent TB. Follow @NetworkVALIDATE on Twitter for all this and more - and take part in BCG100 by using the hashtag #BCG100.
Published: 14 July 2021